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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 10, Issue 2, March 2014 pp 363-364

Research Article

Comparative Study of Oxidative Stress in Carcinoma Breast Patients and Controls

Deshmukh Pratibha R.¹, Shete Anjali N.², K. D. Garkal³

¹Assistant Professor, ²Associate Professor

^1,2 Department of Physiology, Government Medical College, Aurangabad, Maharashtra, INDIA.

Academic Editor : Dr. Aher K. R.

In the scenario of increasing evidence of cancers, the aim of the study was to evaluate the role of oxidative stress in breast cancer. For that purpose, 40 carcinoma breast cases and 40 age, sex matched controls were evaluated for serum MDA levels as an index of lipid peroxidation. The observations revealed that mean serum MDA in these cases was (12.1350± 0.104) nmol/ml while in controls it was (2.422± 0.709) nmol/ml. There was a rise in serum MDA levels in test group as compared to the control group which was statistically highly significant. The high levels of serum MDA indicate increased lipid peroxidation in carcinoma breast cases.