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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 9, Issue 2, December 2013 pp 197-198

Research Article

A Study of 24 Hour Urinary Calcium, Phosphorus and Uric Acid Levels in Normal Subjects and Patients with Urolithiasis

Manjusha D. Hivre^*, Dhananjay V. Bhale^**, Ashlesha A. Bujurge^***, Roshan K. Mahat^***

^*Professor and HOD, ^**Assistant professor, ^***PG Students, Department of Biochemistry

Academic Editor : Dr. Aher K.R.

Background: Urinary stone formation is a common health problem worldwide. All forms of calculi are found in the renal and urinary tract of patients. Renal calculi are most commonly found in adults as compared to children. Objective: The aim of this study was to identify the level of calcium,phosphorus and uric acid in the urine of patients with urinary stones. Methods: The study was conducted over a period of six months (from march to August 2013). It is a descriptive cross sectional study. 24 hours urinary calcium, phosphorus and uric acid levels were determined with the help of Dimension rxL fully auto analyser using the kits supplied by Siemens. Data was collected from 60 subjects. Results: The prevalence of urolithiasis in male patients was 63.3% and 36.7 % in female patients (p<0.05). 24 hour urinary calcium in patients and control was 315±102.5 and 255±175.3 (p<0.03). urinary phosphorus levels in patients with stones were stastically significant (330± 112.3). Conclusion: Higher levels of urinary calcium was found in patients with urolithiasis in this subjects. Urine phosphorus levels were also statistically significant.