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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109


Volume 3, Issue 2, 2012 pp 44-48


Research Article


Histogenesis of Kidney in Human Fetuses

Sadiqali Abbasali Syed1, Rajani Anil Joshi2,N.G.Herekar3

{1Assistant Professor, 2Associate Professor, 3Professor and Head}

Department of Anatomy, Government Medical College, Miraj, District-Sangli (MS) INDIA.

Academic Editor:  Dr. Aher K. R.



The development of kidney is a very complex process having two parts, collecting part and excretory part. The collecting part develops from ureteric bud while excretory part develops from metanephric blastema. Information about development of kidney given in different text books of embryology does not include the details of microscopic appearance of various structures of kidney and its maturation at different gestational ages. The embryologists have not taken into account the histological details of various stages of glomerular development. The aborted human fetuses between 14- 40 weeks of gestational age with no obvious congenital anomalies were obtained. Kidneys were removed and histological slides of 7 microns were prepared and stained with Haematoxylin and Eosin method. The kidney lobules were observed at 14 weeks and after 18 weeks of gestation they diappeared. In the cortex, nephrogenic zone giving rise to new glomeruli was seen up to 37 weeks. Glomeruli passed through various stages of development. Proximal convoluted tubules and distal convoluted tubules were first identified at 20 weeks of gestation. Well differentiated medulla was seen after 24 weeks.