Kidney in Human Fetuses
Syed1, Rajani Anil Joshi2,N.G.Herekar3
Professor, 2Associate Professor, 3Professor and
Anatomy, Government Medical College, Miraj, District-Sangli (MS) INDIA.
Academic Editor: Dr.
Aher K. R.
The development of
kidney is a very complex process having two parts, collecting part and
excretory part. The collecting part develops from ureteric bud while
excretory part develops from metanephric blastema. Information about
development of kidney given in different text books of embryology does
not include the details of microscopic appearance of various structures
of kidney and its maturation at different gestational ages. The
embryologists have not taken into account the histological details of
various stages of glomerular development. The aborted human fetuses
between 14- 40 weeks of gestational age with no obvious congenital
anomalies were obtained. Kidneys were removed and histological slides of
7 microns were prepared and stained with Haematoxylin and Eosin method.
The kidney lobules were observed at 14 weeks and after 18 weeks of
gestation they diappeared. In the cortex, nephrogenic zone giving rise
to new glomeruli was seen up to 37 weeks. Glomeruli passed through
various stages of development. Proximal convoluted tubules and distal
convoluted tubules were first identified at 20 weeks of gestation. Well
differentiated medulla was seen after 24 weeks.