for Sickle Cell Disorders
R. D. Hanmante1,
S. W. Chopade2, K. S. Dhumure2, S. Shere3,
R. S. Bindu4
Professor, Dept. of Pathology, Dr Shankarrao Chavan Govt. Medical
College, Nanded (MS) INDIA.
Dept. of Pathology, Govt. Medical College, Aurangabad (MS) INDIA.
Professor, Dept. of Pathology, Govt. Medical College, Aurangabad (MS)
& Head, Dept. of Pathology, Govt. Medical College, Aurangabad (MS)
Academic Editor: Dr.
500 newborns (age
group 0 � 1 month) were screened using the sickle cell short programme
kit by HPLC. First the blood samples of newborns were subjected for CBC.
The neonates having low haemoglobin content [i.e. Hb < 14 gm %] were
subjected for High Performance Liquid Chromatography (HPLC) study. Out
of 500 newborns, 8 (1.6%) cases were sickle cell trait with male 6 (75%)
preponderance with the more common clinical presentation of fever.
Sickle cell trait was more prevalent in Bouddha 3 (37.5%) community
followed by Muslim 2 (25%) and Matang 2 (25%). Hb S gene is also found
in Banjara community 1 (12.5%).