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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 10, Issue 1, February 2014 pp 51-52

Research Article

Study of Malondialdehyde (MDA) As a Marker of Oxidative Stress in Obese Male Individuals

 

Dhananjay Vasantrao Bhale*, Dhanashri Shashikant Patil**, Roshan Kumar Mahat**

*Professor and HOD, **PG Student, Department of Biochemistry, MGM Medical College, Aurangabad, Maharashtra, INDIA.


Academic Editor : Dr. Aher K.R.

Abstract

 

Background: Obesity is associated with enhanced lipid peroxidation. Malondialdehyde (MDA), one of several by-products of lipid peroxidation process, is a biomarker that provides an indication of lipid peroxidation level. The objective of the present study was to estimate the level of MDA in obese individuals. Methods: 30 obese men with BMI between 25-30 Kg/m2 and 30 non-obese men with BMI <25 Kg/m2 were enrolled in the study. Malondialdehyde (MDA) was assessed in both the groups. Results: Plasma MDA activity was significantly increased in the obese subjects when compared with controls. Conclusion: This finding suggests that obesity is an important factor for enhanced oxidative stress in individuals.