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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 10, Issue 1, February 2014 pp 04-06

Research Article

Chronic Alcoholism and its Effect on Nerve Conduction Velocity


Sangita.R.Phatale1, Anjali Shete2

1Professor and HOD. Dept. of Physiology, MGM’S Medical College Aurangabad, Maharashtra, INDIA.

2Associate Professor. Dept of Physiology, Govt. Medical College, Aurangabad, Maharashtra, INDIA.


Academic Editor : Dr. Aher K.R.



Background and objective: Alcoholism is common and serious problem. Alcohol most commonly consumed in the form of ethanol. The effects of alcohol are mainly caused by altering the function of membrane proteins in many different cell types especially cells of GIT, urinary tract, cardiovascular and nervous system. Alcohol also causes alcoholic peripheral neuropathy.Material and Methods: The study was conducted in the department of physiology MR Medical College Gulbarga. The study was conducted in chronic alcoholic’s subject and there age matched control and in three groups of 30 subjects in each groups. Group I – Normal healthy control, Group II – chronic alcoholic without neuropathy, Group III – chronic alcoholic with neuropathy. Nerve conduction study was carried out by using RMS- EMG,EP machine manufactured by Recorders and Medicare System (P) Ltd. The data was statistically analyses by using student unpaired’ test.Result: Motor and sensory nerve conduction velocity was compared with chronic alcoholic and healthy aged matched controls. The both sensory and motor nerve conduction was significantly decreased in chronic alcoholic without neuropathy and with neuropathy.Conclusion: From our study we conclude that alcohol addiction has adverse effect on the NCV Thus helps in early diagnosis as well as prognosis of alcoholic neuropathy