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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 10, Issue 1, February 2014 pp 85-88

Research Article

Working and Short Term Memory Status of Male and Female Patients in Type 2 Diabetes Mellitus

Sanjay B. Bhagoji¹, Mahesh Patil², Mrutyanjay Mirje³, Mallikarjun Biradar⁴

¹Department of Physiology, K.V.G Medical College and Hospital, Kurunjibhag, Sullia, Karnataka, INDIA.

²Department of Pathology, B.K.L Walawalkar Hospital Research and Diagnostic Centre, Dervan, Ratnagiri, Maharashtra, INDIA.

³Department of Pharmacology, Institute of Medical Science and Research, Mayni, Satara-415102, Maharashtra, INDIA.

Academic Editor : Dr. Aher K.R.

Background and objectives: Working and short term memory loss is common in diabetic patients. Though cognitive deficits affect daily activities and differences between genders are not given much importance to assess working and short term memory at bedside. Hence this study was undertaken to compare working and short term memory in type 2 diabetics with gender matched normal subjects. Methodology: Present study was conducted in Al-Ameen Medical College and Government district Hospital, Bijapur on 114 diabetics (male=72, female=42) and 119 normal subjects (male=79, females=40) aged (40-60 yrs.). Cognitive function assessment was done for short term and working memory by using 5 memory tests-AVLT, VFT, VRT, WDST and VST were used. The results were expressed in average total scores (%). χ² test was used for statistical analysis. Results: Memory scores of all 5 tests decreased in male diabetic patients when compared to normal male subjects and this decrease was statistically significant (P<0.0001). When female diabetes patients were compared with normal female subjects out of 5 memory tests memory scores in 4 tests were decreased (except VRT) and this decrease was found to be statistically significant (P<0.05). Male diabetic patients when compared with female diabetic patients, decrease in memory scores in male diabetic patients was found to be statistically significant in all tests (except in WDST). Interpretation and conclusion: The short term and working memory status in the present study decreased significantly in the male diabetic patients, which may be due to hyperglycemia, hypoglycemia, vascular dementia and insulin resistance, type of diabetes, age of onset, duration and type of therapy. Therefore these observed effects of gender are of potential clinical importance because working and short term memory loss may interfere with day today activities.