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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 10, Issue 1, February 2014 pp 172-173

Research Article

Assessment of the Diagnostic Accuracy of Thyroid Lesions by FNAC


K. Sathiyamurthy1, Mahesh S. Patil2, Mrutyunjay Mirje3

1Assistant Professor, Department of Pathology, Vinayak Mission’s Krupanand Variyar Medical College, Seeragapadi, Salem.

2Assistant Professor, B K L Walawalkar rural medical College Kasarwadi Tq: Chiplun. Maharashtra, INDIA.

3Assistant Professor, Department of Pharmacology, IMSR, Mayani. Satara, Maharashtra, INDIA.

Academic Editor : Dr. Aher K.R.



Introduction: Fine needle aspiration cytology has become an accepted and cost effective procedure for rapid diagnosis of thyroid lesions It’s a simple, noninvasive technique with minimal complications. This procedure was firmly established as an important test for the evaluation of thyroid disease and an effective test for the preoperative diagnosis of thyroid nodule. Objectives: To assess the diagnostic accuracy [sensitivity, specificity, positive predictive value (ppv) and negative predictive value(npv)]. Materials and Methods: During the prospective study, 110 fine needle aspiration of thyroid was performed during a period of two years (2008-2010) in department of pathology, Navodaya Medical College, Raichur. Cytological diagnoses were classified diagnostically, and histological and cytological correlations were determined and diagnostic accuracy of FNAC in thyroid lesions is studied and statistical analysis was performed. Results: Out of the 110 patients studied, 100 cases were of non neoplastic thyroid lesions, 10 were neoplastic. In Histopathological examination of non neoplastic category out of 5 cases 1 were diagnosed as follicular adenoma which were diagnosed as nodular goitre by FNAC. In neoplastic category 4 showed follicular adenoma and 2 cases as nodular goitre out of 6 which was diagnosed as follicular neoplasm in FNAC. Papillary carcinoma (3 cases) and medullary carcinoma (1 case) were diagnosed same as FNAC results. Interpretation and Conclusion: By comparing the results of FNAC and histopathology, FNAC has sensitivity of 88.88% and specificity of 66.66% in the diagnosis of malignant thyroid diseases. Although histopathology is a gold standard procedure, FNAC of thyroid lesions has got good sensitivity and specificity.