Home| Journals | Statistics Online Expert | About Us | Contact Us

    About this Journal  | Table of Contents

[Abstract] [PDF] [HTML] [Linked References]

International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 10, Issue 1, February 2014 pp 187-188

Research Article

Clinical Presentation and Histological Evaluation of Endometrium in Perimenopausal Uterine Bleeding


Shazia Anjum1, Suresh Gawai1, Rekha Mudkhedkar2, Padma Bakal3, Bindu RS5, Badaam Khaled M5, Bhople KS6

{1Assistant Professor, 4Professor and Head, Department of Pathology}{5Assistant Professor, Department of Physiology}{6Dean}

Government Medical College, Aurangabad, Maharashtra, INDIA.

2Pathologist, Civil Hospital, Jalna, Maharashtra, INDIA.

3Pathologist, Civil Hospital, Nashik, Maharashtra, INDIA.

Academic Editor : Dr. Aher K.R.



Introduction: Perimenopause is the phase of the life of a woman when her body makes a shift from ovulatory cycles and menstruation towards a stage of permanent infertility called as menopause. Abnormal uterine bleeding is a common reason for women of this age group to consult their gynaecologist.  Methods: Total 200 cases of perimenopausal uterine bleeding in women above 40 years of age were studied. 110 Endometrial samples were obtained from Dilatation and Curettage and 90 samples from hysterectomy cases. Results: Maximum number of cases presented with clinical features of menorrhagia (91.5%), followed by metrorrhagia (2.5%), dysmenorrhoea (3%), Leucorrhoea (2%) and pyometra (1%) constituting the rest of the cases. Histological analysis showed Proliferative endometrium to be the most common finding seen in 118 cases (59%) as a cause of perimenopausal uterine bleeding. Hyperplastic endometrium was the second most common cause observed in 32 (16%) cases followed by secretory endometrium in 23 (11.5%) cases. Atrophic endometrium was observed in 10 (5%) cases. Irregular endometrium was found in 8 (4%) cases. Endometrial polyp was observed in 4 (2%) cases and endometrial carcinoma in 4 (2%) cases. Chronic non-specific endometritis was found in a single case during this study. Conclusion: Uterine bleeding in the perimenopausal women is commonly dysfunctional in origin. Also, there underlying organic pathologies found which signify the importance of endometrial curetting and biopsy in the evaluation.