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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109
Volume 10, Issue 3, April 2014 pp 423-429
Synthesis, Structure, Spectroscopy and Antimicrobial Activity of Copper (II) Complex of Furfuraldehyde-2-Salisaldehyde Thiosemicarbazide1-(2-ydroxybenzylidene)-4-((4H-pyran-2-yl) methylene) Thiosemicarbazide
Shobha S. Borhade
Department of Drug Chemistry, S. M. B. S. T. College, Arts, Science and Commerce, Sangamner Affiliated to University of Pune, Sangamner Dist. Ahmednagar, Maharashtra, INDIA.
Academic Editor : Dr. Aher K.R.
Cu(II) complexes containing ligand Furfuraldehyde-2-Salisaldehyde thiosemicarbazide 1-(2-hydroxybenzylidene)-4-((4H-pyran-2-yl)methylene) thiosemicarbazidehavebeen synthesised. The ligands were characterised on the basis of Elemental Analyses, Absorption spectra,IR, NMR,X-RD,Massspectalstudy and Antimicrobial Activity. A simple ,sensitive and specific spectrophotometric method for the determination of Cu(II) is developed based on the colour reaction between copper (II) and Furfuraldehyde-2-Salisaldehyde thiosemicarbazide 1-(2-hydroxybenzylidene)-4-((4H-pyran-2-yl)methylene) thiosemicarbazide .Physico-chemical and Analytical characteristic of ofcopper (II) and Furfuraldehyde-2-Salisaldehyde thiosemicarbazide1-(2-hydroxybenzylidene)-4-((4H-pyran-2-yl)methylene) thiosemicarbazidewas studied. Degree of dissociation,Dissociation constant and Stability constant of complex are 0.0476,9.5078x10-13 , and 1.0517x1012 respectively. The change in free energy of the complex was -68.59 KJ/mole.Composition of the metal and ligand has been determined by job’s variation and mole ratio methods. The optimum conditions for complete colour development have been established by studying parameters ike effect of medium,reagent concentration, time period have been studied. Effects of diverse ion have been studied.