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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 11, Issue 1, May 2014 pp 83-86

Research Article

Effectiveness of the First Antiepileptic Drug in the Treatment of Epilepsy in Children


Sangeeta Basu1, C D Aundhakar2, Jitendra Kumar3, Amit Galgali4, Rakesh Patil5, Sharanabasav Kirdi6

1, 3,4,5,6Resident, 2Professor, Department of Pediatrics, Krishna Institute of Medical Sciences Deemed University, Karad, Maharashtra, INDIA.

Academic Editor : Dr. Aher K.R.



Seizures are the most common pediatric neurologic disorder, with 4% to 10 % of children suffering at least one seizure in the first 16 years of life. 3 If the response of the first antiepileptic drug trial is a powerful marker of outcome, then the early identification of patients who are at risk to fail the initial antiepileptic drug trial should be a priority. The AED chosen for the initial therapy should be one that is for the highly effective for the particular seizure type or syndrome and that is safe and well tolerated. We conclude that presence of history of seizures in family members and the presence of microcephaly can have a significant role to play in the outcome of the trial with the first AED. Good seizure control can be achieved by using mono therapy with the standard first line AED drugs in moderate doses.