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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 11, Issue 3, July 2014 pp 270-276

Research Article

Periodic prevalence of various STDs and its correlation with cervical dysplasia

Ishita Ghosh1, Shaswati Chaki2

1Assistant Serologist and Chemical Examiner to Govt of India, In charge Regional STD Reference Laboratory, Institute of Serology, Kolkata, INDIA.

2 HIV Research Fellow, Regional STD Reference Laboratory, Institute of Serology, Kolkata, INDIA.



Introduction: Sexually transmitted infections (STIs) constitute an important public health problem worldwide and contribute to increasing morbidity and mortality due to their association with Human Immunodeficiency virus and for predisposing to cervical dysplasias. STIs can be caused by transmission of bacteria, virus, fungi or protozoa and most of these can be controlled by early detection, appropriate medication and health education. Materials and Methods: In a Regional Reference STD laboratory in West Bengal, samples from 2143 female patients with chief complain of vaginal discharge, were tested for detection of three STIs namely Trichomonas vaginalis, Candida species and Treponema pallidum .Concomitantly, study of cervical cytology on Papanicolaou stained smears was carried out in all cases. The study period extended over four years. Trichomoniasis was identified by wet mount and culture, Candida by culture and Gram staining, Syphilis by Venereal Disease Research Laboratory (VDRL) and Treponema Pallidum Haemagglutination (TPHA) test. The cytological findings were interpreted according to Bethesda 2001 classification. Results: The majority of the patients belonged to the age group of 25 to 44 years and Hindus outnumbered Muslim. The percentage positivity of Syphilis has decreased over the last four years whereas Candida and Trichomonas infections demonstrated a rising trend. Candida and Trichomonas infection were frequently associated with cervical dysplasia which was not observed in case of Syphilis. Conclusion: Screening programmes incorporating cervical cytological study and tests for detection of different STIs will help facilitate early and effective intervention necessary for preventing progression of STI and development of cervical dysplasia.