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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 12, Issue 1, September 2014 pp 69-72

Research Article

Comparative analyses of cavity effusions by cell blocks and smear examination

Richa Nathani1, Rakesh Singh Hazari2, Yogesh G. Patle3, Santosh Gupta4

1PG student, 2Professor, 3Assistant Professor, 4Professor and HOD, Department of Pathology, PCMS and RC, Bhopal, Madhya Pradesh, INDIA.

Background: The cytological examination of serous effusions has increasingly gained acceptance in clinical medicine, to such an extent that a positive diagnosis is often considered the definitive test and obviates exploratory surgery1. Cell block study is valuable in cytopathology because it provides histopathologic correlation and additional material for immunohistochemical studies2. Aim: To study cavity effusions and to compare fluid smear cytology (CS) and cell block (CB) as diagnostic methods Material and Method: The study was conducted in the Cytology section of the Department of Pathology. Fourty serous fluids were subjected to diagnostic evaluation in a period of nine months. Conventional smears and cell block using 10% alcohol: formalin fixative, were prepared. After the Cytological diagnosis, each case was objectively analysed as per the point scoring described by Mair et al. Statistical analysis was done. Results: Cellularity and additional yield for malignancy was found by CB method. Conclusion: With CB technique positive results were increased and demonstrated better architectural patterns which were helpful in approaching the correct diagnosis of the primary site.