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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 12, Issue 1, September 2014 pp 82-85

Research Article

Study of various antenatal factors associated with congenital anomalies in neonates born at tertiary health care center

Shakira Vijay Savaskar1, Shivprasad Kachrulal Mundada2, Asadkhan Sahebkhan Pathan3,

Sonal Fulchand Gajbhiye4

1Professor and Head, 2,3Assistant Professor, 4Post Graduate Resident, Dept. of Paediatric, Government Medical College, Latur, Maharashtra INDIA.


Introduction: An anomaly is a structural feature that departs from normal. Congenital refers to an anomaly, which is present at birth but does not indicate whether the cause is genetic or non-genetic. It is suggested that the most of the common malformation in human have mixed genetic and environmental causation. It is clear that although the exact causology of the great majority of human congenital malformations is uncertain, the role of genetic and environmental factors cannot be doubted. Aims and Objectives: to study the various factors associated with congenital anomalies in neonates born at tertiary center. Materials and Method: All the live born and still born babies born in the GMC Latur were observed meticulously to diagnose congenital anomalies. Age and parity of the mother was recorded on a prestructured proforma. Also various factors such as history of folic acid tablets supplementation, anemia, abortion and hydrominos was recorded. History of fever, consumption of drugs and preeclampsia in the present pregnancy was also recorded. Results: Incidence of congenital anomalies was found to be 43.03 per 1000. Incidence was increasing as the age of mother and parity was increasing. Maximum numbers (13.9%) of anomalies were diagnosed in mother more than 30 years of age. Mother who had not taken folic acid supplementation in antenatal period had maximum chance of developing congenital anomalies (37%). Congenital anomalies were also common in anemic mothers (31%). Fever during first trimester was reported in 11.5% cases. 16% women reported to be suffering form polyhydominos. Conclusion: Incidence of congenital anomalies was higher in stillborn as compared to live born neonate. Increasing maternal age and birth order is associated with increased incidence of congenital anomalies. Majority of mothers with congenital anomalous neonate did not receive regular folic acid supplements.