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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 12, Issue 1, September 2014 pp 102-104

Research Article

Investigation of acid base status in organo-phosphorus poisoning cases

Dudekula Moulali1, D.V.H.S Sarma2, Narumalla Jagannath3, T. Veeresh4, K. Eshwar Reddy5

{1,5Tutor,2Professor and Head, 4Assistant Professor, Department of Biochemistry} {3Tutor, Department of Pharmacology}

S.V.S Medical College, Yenugonda, Mahabubnagar, Telengana – 509001 INDIA.

Introduction: Organophosphate (OP) compounds have been used worldwide for pest control for over 100 years. They are the insecticides of choice in the agriculture world and are the most common cause of poisoning among the organic insecticides. Varity of complication are being seen in the patients of OP poisoning. Which are supposed to be due to the changes in the acid base status. Aims and objectives: to study the acid base status in organo phosphorus poisoning cases Materials and Method: in the present study 20 cases of OP poisoning were studied. Arterial blood was collected to analyze the acid base status of these patients. Acid Base analysis of ABG report includes PH, PCO2, PO2, HCO3-, SO2%, BEB, Hb, BE-ECF, HCt, A and a/A. Estimation of these parameters was done by using “Arterial blood gas analyzer. Results: Out of 20 OP poisoning patients included in the study 7 were females 14 were males. The age group most of the people belong to 20 – 45 years. Majority of the cases were of respiratory alkalosis (65%), followed by respiratory acidosis (15%) and metabolic alkalosis (5%). No cases showed metabolic acidosis in the study. 15% cases showed normal acid base status in the study. Conclusion: Vide variation was seen in the acid base status of patients of OP poisoning. And it is also essential to identify the complications and manage them accordingly.