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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 12, Issue 1, September 2014 pp 105-109

Research Article

Sero-prevalence of transfusion transmissible infections and co-infections among blood donors in a tertiary care hospital of the capital:

three and half year study

Shruti Dogra1, Oneal Gupta2, Manisha S. Singh3, D. S. Rawat4

1,2,3Senior Resident, 4Associate Professor, Department of Pathology, Vardhaman Mahavir Medical College, Safdarjung Hospital, New Delhi, INDIA.

Introduction: This study is conducted to evaluate the seroprevalence of HBV, HCV, HIV and syphilis among blood donors in a tertiary care hospital of New Delhi, India a three and half year experience. A retrospective study of donor records covering the period between Jan 2009 to June 2012 at the blood bank, Safdarjung hospital and VMMC, New Delhi was carried out. All samples were screened for HIV, HBsAg, HCV and syphilis. Out of a total of 95,185 blood donors, 29433 were voluntary donors and the remaining 65,752 were replacement donors. Seroprevalence of HBV, HCV and HIV was studied by ELISA in voluntary and replacement blood donors. RPR was done for screening of syphilis. The seroprevalence of HBV was highest 2.4% followed by HIV and HCV 0.72% and 0.7% respectively. That of syphilis was found to be 0.48%. In all the markers tested there was increased prevalence of TTI among the replacement donors (3.06%) as compared to voluntary donors (1.25%). Blood units having more than one sero reactive infection were 70 (0.07%) in number.. Among HIV seropositive donors 24 were positive for HCV, 18 for HBV and 9 for VDRL. Thus, transmitted transfusion infections as well as co infections are a major hurdle in safe blood donation practise in the capital. Strict and stringent donor criteria and use of sensitive screening tests as well as encouragement of voluntary donations is the need of the hour.