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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 12, Issue 2, September 2014 pp 219-222

Research Article

Glycosylated proteins (fructosamine) and albumin levels in diabetic patients after multi-vitamin multi-mineral supplementation

Bhushan Mahajan¹, S. K. B. Patil², Vaishali Mahajan³

¹Assistant Professor, Department of Biochemistry, Government Medical College and Hospital Nagpur, INDIA.

²Professor and HOD, Department of Biochemistry, Chhattisgarh Institute of Medical Sciences, Bilaspur, Chhattisgarh, INDIA.

Introduction: Prolonged hyperglycemia is known to cause an increase in levels of non enzymatically glycosylated proteins which is thought to contribute to long term complications of disease by enzyme inactivation, inhibition of binding of regulatory molecules, decreased proteolysis and cross-linking of glycated proteins. In present study, fructosamine and albumin levels were measured in normal healthy controls and Diabetic patients before and after supplementation of Multi-vitamin multi-mineral tablets. Serum fructosamine level was decreased significantly in diabetic patients after multi-vitamin multi-mineral supplementation.