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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109
Volume 12, Issue 2, September 2014 pp 233-235
Platelet aggregation, plasma fibrinogen level and euglobulin clot lysis time in male hypertensive patients
Shekhar P Shiradhonkar1, Aradhana Arvind Deshmukh2, S M Handergulle3
1Nephrologist, Manik Hospital, Aurangabad, Maharashtra, INDIA.
2Assistant Professor, Department of Physiology, MGM Medical College, Maharashtra, INDIA.
3Associate Professor, Department of Physiology and Medicine, S. R. T. R. Medical College, Ambajogai, Beed, Maharashtra, INDIA.
Introduction: The present study was conducted at S. R. T. R. Medical College, Ambajogai. Fifty hypertension cases and 50 controls were taken according to different age groups. Platelet aggregation, plasma fibrinogen level and euglobulin clot lysis time were compared with age matched control and also cases were compared amongst themselves depending upon the duration of hypertension. Analysis of results showed a statistically significant increase in platelet aggregation and plasma fibrinogen level in all the hypertensive cases when compared with age matched control. Euglobulin clot lysis time showed a statistically significant decrease (increase in fibrinolysis) in all the hypertensive cases when compared with age matched control. When the increase in Euglobulin clot lysis time (decrease in fibrinolysis) was correlated with duration of hypertension, it was found that the decrease in fibrinolysis varies directly with increase in duration of exposure.