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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109
Volume 14, Issue 3, April 2015 pp 584-586
Research Article
Clinical and hematological profile of pancytopenia in children in rural tertiary care hospital
Chate Sambhaji C1, Kagne Swati S2
{1Assistant Professor, Department of Paediatrics} {2Assistant Professor, Department of Obstetrics and Gynaecology}
Swami Ramanand Teerth Rural Government Medical College and General Hospital, Ambajogai, Maharashtra, INDIA.
Abstract
Introduction: Pancytopenia is a common occurrence in paediatric patients. The etiology of pancytopenia in children is varied, ranging from nutritional and infectious causes to aplasia and marrow infiltration by fatal malignancy. Knowing the exact etiology is helpful for specific treatment and prognostication. Aim: To evaluate the etiological and clinico-hematological profile of children with pancytopenia Methods: This study was carried out in rural tertiary care hospital over a period of 1 year. Children with pancytopenia from 3 month of age till 12 years of age were included in the study. Complete hemogram, reticulocyte count, Peripheral smear, bone marrow aspiration and bone marrow trephine biopsy were performed. Result: Forty-six patients from 3 month of age to 12 years of age were studied. Fever (67.3%) was the most common presenting symptom followed by pallor (63%). The most common cause of pancytopenia in children was found to be megaloblastic anaemia (30.4%), followed by aplastic anaemia (26%) and malignancy (19.5%). Conclusion: The megaloblastic anaemia is most common cause of pancytopenia in children in our study followed by aplastic anaemia and acute leukaemia.
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