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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 15, Issue 1, May 2015 pp 59-61

Research Article

Comparative study of serum magnesium and copper levels in type 2 diabetes mellitus patients and non diabetic healthy subjects

Deepali Tonde¹, Bhushan Mahajan², Manohar Muddeshwar³, Sandip Lambe⁴

¹Junior Resident, ³Professor and HOD, ⁴Assistant Professor, Department of Biochemistry, Government Medical College, Nagpur, Maharashtra, INDIA.

²Associate Professor, Department of Biochemistry, Government Medical College, Aurangabad, Maharashtra, INDIA

Abstract
Diabetes mellitus is a common complication of chronic pancreatitis, can disturb the metabolism of zinc, copper, magnesium and selenium¹. The serum magnesium and copper levels were estimated in sixty patients admitted in medicine department in GMC, Nagpur and in non diabetic healthy subjects. The result of study showed that serum copper were increased and magnesium level were decreased significantly in diabetic group compared to non-diabetic group. Thus it is concluded that these changes play an important role in the pathogenesis of type 2 DM by the involvement of these elements in the oxidative stress and may have a contributory role in the progression of DM and later development of complications.