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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 15, Issue 1, May 2015 pp 65-67

Research Article

Oxidative stress in patients with beta thalassemia major

Vinita Belsare1, Hrishikesh Belsare2, Sarika Munghate3, Sandip Lambe4

1,3,4Assistant Professor, Department of Biochemistry, Government Medical College, Nagpur, Maharashtra, INDIA.

2Associate Professor, Department of Paediatrics, Chirayu Medical College, Bhopal, Madhya Pradesh, INDIA.

Abstract
Thalassemia major is cause of severe anemia. Anemia is treated with repeated blood transfusion. All this leads to ineffective erythropoiesis and hemochromatosis. The present study was conducted to assess the severity of anemia and iron overload due to repeated blood transfusion leading to oxidative stress.