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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 15, Issue 2, June 2015 pp 287-289

Case Report

Signet ring stromal tumor of ovary - Report of an unusual case

Soumya Kundu1, Narendranath Hait2, Priyaranjan Chattopadhyay3, Taraknath Saha4, Anjon Debnath5

{1Demonstrator, Department of Pathology} {2Assistant Professor, Department of Gynaecology and Obstetrics} {3Assistant Professor, 4Assosiate Professor, Department of Pathology} Midnapore Medical College and Hospital, Medinipur, West Bengal, INDIA.

5Senior Consultant, Department of Pathology, Neotia Getwel Healthcare Centre-Siliguri, West Bengal, INDIA.

Signet-ring stromal tumor is a rare ovarian neoplasm, only a few cases being reported in the English literature. We report a case of SRST of the right ovary in a 67-year-old woman who presented with abdominal discomfort and underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy. The right ovary showed a part solid part cystic mass 12.5 cm in maximum diameter. On histopathologic examination, the tumor was composed of small round and oval cells with cytoplasmic vacuolization and a typical signet-ring appearance, focally admixed with fibromatous tissue. Special staining revealed that the vacuoles of the tumor cells contained no lipid, mucoprotein, or glycogen. The patient remains free of disease six months after surgery. Signet-ring tumor of the ovary is a rare variant of benign ovarian sex-cord stromal neoplasm and should be distinguished from Krukenberg tumor, the most important differential diagnosis.