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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109
Volume 15, Issue 3, July 2015 pp 530-532
A histopathological study of lichen planus in Indian population
Gautam Goyal1, Jayaprakash C S2, Salman Akhter3
1,3PG Student, 2Associate Professor, Department of Pathology, Father Muller Medical College, Mangalore, Karnataka, INDIA.
ichen planus is an idiopathic subacute or chronic inflammatory disease of the skin, mucous membranes and nails. Exact pathogenesis of lichen planus is still unclear. We studied the histopathological profile of lichen planus in indian population. A total of 40 cases of histologically diagnosed lichen planus samples were included. Clinical features like age, sex, site of lesion were noted from the case record form. Histological features of lichen planus were studied.statistical analysis chi square test and fisher’s exact test was used to assess associations between various variables. Peak incidence was seen at 3rd decade with 8/40 (22.5%) cases. The most commonly involved site of lesion being lower leg with 16/40 (40%). Most common histological finding was formation of civette bodies with 35/40 (87.5%) followed by hyperkeratosis 33/40(82.5%) and pigment incontinence 34/40 (72.5%). Lichen planus is a disease of adults (20–40years) according to western data, but in Indian population it is also common. Classical lichen planus has a strong association of involvement of the lower limbs in the younger age group. Involvement of upper limb is more common in female patients in lichen planus.