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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109
Volume 15, Issue 3, July 2015 pp 542-543
Case Report
Anaesthetic management of modified radical mastectomy in a patient with carcinoma breast with Bernard–Soulier syndrome
Namrata Ranganath1, V B Gowda2, Kavitha Lakshman3, Arthi B H4
1,2Associate Professor.,3,4Assistant Professor, Department of Anaesthesiology and Pain relief, Kidwai Memorial Institute of Oncology, Bangalore, Karnataka, INDIA.
Abstract
Bernard-Soulier syndrome (BSS) is a rare congenital bleeding disorder characterised by thrombocytopenia, large platelets and a prolonged bleeding time. Patients with Bernard–Souliersyndrome are at risk of severe bleeding. A mutation involving glycoprotein complex 1b-V-IX renders platelets unable to bind Von Willebrand factor (vWF) and form clots. Patients often report spontaneous epistaxis, bleeding gums or heavy menstrual periods. Bernard–Soulier syndrome patients require rigorous perioperative planning.1 We present a female patient with BSS that underwent bilateral modified radical mastectomy for her bilateral carcinoma breast. Search words: giant platelet syndrome, Bernard–Soulier syndrome, breast cancer, bleeding diasthesis, peri operative management.
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