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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109
Volume 15, Issue 3, July 2015 pp 561-566
A study of reliability of shake test in the estimation of the fetal maturity
Professor and HOD, Department of OBGY, IMDR, Mayani, Satara, Maharashtra, INDIA.
Background: It is thought that babies with respiratory distress syndrome (R.D.S.) have insufficient pulmonary surfactant. This surface active lecithin in the pulmonary secretion contributes to the amniotic fluid and its analysis accurately reflects the degree of lung maturity. Lecithin-sphingomyelin ratio (L/S ratio) in amniotic fluid tells us about lung maturity reasonably accurately. However, estimation of L/S ratio needs help of elaborate laboratory facilities which may not be possible in developing countries especially in rural areas. So there is a need to develop simple bedside clinical test to assess fetal lung maturity. Shake test is a rapid, simple, bedside, inexpensive test giving us as good a result as L/S ratio. Objective: Present study was done to assess the reliability of shake test in the estimation of fetal pulmonary maturity. Methods: This prospective study was carried out over a period of one and a half years (April 2014 to Dec. 2014). 80 cases (40 high risk and 40 without high risk factors) were included in this study group. The shake test was carried out on amniotic fluid sample obtained by ultrasonography guided transabdominal or transcervical amniocentesis. The false positive and false negative results of Shake test were critically analysed. Results: Shake test results revealed improvement in fetal pulmonary maturity with advancement of gestational age in 80% of cases. It was observed that positive Shake test correlates well with fetal pulmonary maturity as the incidence of R.D.S. was very low (2.77%) in cases with positive Shake test. However, negative Shake test result does not confirm fetal pulmonary immaturity, because even with negative shake test result, only 39.29% of newborns developed R.D.S. Conclusions: Shake test is a simple bedside inexpensive test requiring less laboratory facilities, thus useful in rural set ups. Positive shake test result correlates very well with fetal pulmonary maturity.