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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 15, Issue 3, July 2015 pp 587-591

Research Article

Effect of myopia on thickness of retinal nerve fiber layer as measured by optical coherence tomography

Atanu Biswas1, Mahuya Pal Chattopadhyay2, Ritesh Singh3, Asim Ghosh4

{1Assistant Professor, 2Associate Professor, Department of Ophthalmology} {3Associate Professor, Department of Community Medicine} College of Medicine and JNM Hospital, WBUHS, Kalyani-741235, West Bengal, INDIA.

4Professor, Regional Institute of Ophthalmology, Medical College, Kolkata, West Bengal, INDIA.

Background: Myopia is associated with a large eyeball in which collimated light produces a focussed image in front of the retina. This study was done to evaluate the relationship of foveal thickness and peripapillary RNFL thickness with myopia in eyes with no other obvious ocular pathology. Methods: Visual Field Analysis was done using static, automated, white-on white threshold perimetry (programme 24-2, Humphrey Field Analyser II, Carl Zeiss Meditec) and Retinal Nerve Fibre Layer Analysis of peripapillary nerve fibre layer and fovea, in dilated pupils, using OCT version 3 (Stratus OCT, Carl Zeiss Meditec Inc.). Results: In total 100 (62 males) myopic subjects were recruited for the study. The degree of myopia was not related with sex, age and foveal thickness of the individuals. The peripapillary retinal nerve fibre layer thickness of superior, inferior, nasal quadrant was significantly different in two groups of high myopic and low-to-moderate myopic group. The average thickness of RNFL was significantly less in high myopic when compared with low-to-moderate myopic group. The RNFL thickness was more in temporal quadrant of high myopic group. The superior, inferior, nasal and average RNFL thickness decreased with negative spherical equivalent. Conclusion: It can be concluded that the thickness of the peripapillary retinal nerve fibre layer decreases as the myopia advances in at least superior, inferior and nasal quadrants.