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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 15, Issue 3, July 2015 pp 610-614

Research Article

Correlative study of lipid profile, fibrinogen level and BMI in Type 2 diabetes mellitus with hypertension

A Manjula1, Devika Madhu2, Chandrashekar3, Someshekar4, Chaitra5, Rashmi6

1Associate Professor, Department of Medicine, K.R. Hospital, Mysore Medical College and Research Institute,

Mysore-570 021, Karnataka, INDIA.

Diabetic hypertensives have higher cardiovascular morbidity and mortality than general population. Various risk factors like age, BMI, hypertension, smoking, dyslipidemia, etc. have been extensively studied, but still these together cannot explain increased cardiovascular morbidity and mortality in diabetes. Several studies have shown that fibrinogen is a powerful independent risk factor for cardiovascular disease. In the present study, fibrinogen levels in 50 diabetic hypertensives were estimated and its relation to BMI and lipid profile parameters was studied. The objectives of this study are: 1) To estimate plasma fibrinogen levels in patients with type 2 diabetes mellitus and hypertension. 2) To correlate plasma fibrinogen with BMI and lipid profile parameters. Higher plasma fibrinogen levels were found in diabetic hypertensives. There was a significantly positive correlation between plasma fibrinogen and BMI. There was a significantly positive correlation between BMI and total cholesterol levels. Diabetic hypertensives have higher fibrinogens levels, which was related to BMI and total cholesterol level in a statistically significant manner.