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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 15, Issue 3, July 2015 pp 448-450

Research Article

Clinical profile of urinary tract infections in diabetes

Eshan Sharma1, Rakesh Thakuriya2, Shwata Acharya3

1,2Assistant Professor, 3Jr. Resident, Department of Medicine, N.I.M.S Medical College and Hospital, Jaipur, Rajasthan, INDIA.

Background: Urinary tract infection (UTI) is the most common infection among patients with Diabetes Mellitus and is found to be responsible for considerable morbidity, especially if it is not recognized or left untreated. Objective: Present study was done to describe the clinical profile of urinary tract infections in diabetes at our hospital. Methods: This is a cross-sectional study of 150 diabetic patients who have visited the hospital for treatment during the study period. Demographic and clinical data were obtained from each participant using questionnaires. Clean-catch, midstream urine samples were collected and cultured for UTI diagnosis and antibiotic susceptibility. Symptomatic bacteriuria was considered as a positive urine culture (≥105 colony-forming units [CFU]/mL of a single bacterial species) from the patients with the symptoms associated with UTI; asymptomatic bacteriuria was defined as positive urine culture from the patients without symptoms associated with UTI. Results and Conclusion: Out of 150 patients, 92 were males and 58 were females. 142 patients had type 2 diabetes mellitus. The prevalence of Urinary tract infections was found to be 22% with 33 cases of UTI among study population. The predominant forms of isolates were Escherichia coli found in 20 cases (60.6%) and Klebsiella pneumoniae in 6 cases (18.2%). E. faecalis isolates were seen in 4 cases and P mirabilis isolates were seen in 3 cases. Five, three, three and two of 20 E. coli isolates showed resistance to ampicillin, nitrofurantoin, co-trimoxazole and amoxicillin-clavulanic acid, respectively. All the E. coli isolates were susceptible to gentamicin and cephalexin. Two, one and one of nine K. pneumoniae isolates were resistant to ampicillin, co-trimoxazole and amoxicillin-clavulanic acid. All the nine K. pneumoniae isolates found to be sensitive to gentamicin (100%)