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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 16, Issue 1, Aug 2015 pp 45-48

Research Article

Does hypovitaminosis D have a role in lipid profile alteration among non-obese diabetics?

Hariharan A1, Asmathulla S2, Suresh S3

{1Post Graduate, 2Professor, Department of Biochemistry} {3Associate Professor, Department of General Medicine}

Sri Manakula Vinayagar Medical College and Hospital, Puducherry, INDIA.

Objective: The prevalence of hypovitaminosis D among diabetics is very high with it being an adjuvant causative factor. It has been shown in few studies that hypovitaminosis D has an impact on lipid profile of diabetic patients but most of the studies haven’t excluded the confounding factor viz. obesity. It is a known fact that obesity has a major role in development of hypovitaminosis D. So in our study, we try to find out whether the association between hypovitaminosis D and lipid profile exists even after excluding obesity in diabetics. Materials and Methods: It is a cross section study conducted in 55 Non-obese diabetics. We had measured serum FBS, vitamin-D, urea, creatinine, lipid profile and urinary microalbumin. Results: We found a negative correlation between vitamin-D with that of TGL (r: -0.337; p<0.012) and VLDL (r: -0.190; p<0.011). There was no association found between hypovitaminosis D with that of cholesterol, HDL and LDL. Conclusion: From our study it’s clear that hypovitaminosis D is associated with TGL and VLDL even after excluding obesity.