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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 16, Issue 1, Aug 2015 pp 24-25

Case Report

Cytodiagnosis of Gouty Tophi – Case report

A D Jungare1, S A Jungare2, U D Suryawanshi3, B B Sonawane4

{1Associate Professor, 3Assistant Professor, 4Professor, Department of Pathology} {2Assistant Professor, Department of Biochemistry} Government Medical College and Hospital, Akola, Maharashtra, INDIA.

Gout is a clinical syndrome which is characterized by hyperuricemia and recurrent acute arthritis. Accumulation of tophi in joints triggers the inflammatory response of gouty arthritis. We report here a case of gouty tophi diagnosed by fine needle aspiration, along with review of literature. A 53 year old male presented with multiple subcutaneous nodules on both feet. The nodules were firm and nontender. Fine needle aspiration was diagnostic as it revealed granular amorphous material and scattered stacks and sheaves of slender needle shaped crystals few histocytes and chronic inflammatory cells. Radiographs of both feet showed extensive soft tissue swellings with underline bone erosion. The serum uric acid levels were found to be raised confirmed diagnosis. Fine needle aspiration is an effective tool in the diagnosis of gouty tophi. Difficulties in management can be avoided by using the fine needle aspiration technique.