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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 16, Issue 2, Sept 2015 pp 385-389

Research Article

A study of asymptomatic bacteriuria in pregnancy

A Mohankumar1, J Kaur2, M Deb3, S Prateek4

1Assistant Professor, Department of Microbiology, PK Das Institute of Medical Sciences, Ottapalam, Kerala - 679522, INDIA.

{2Associate Professor, 3Professor, Department of Microbiology} {4Professor, Department of Obstetrics and Gynecology}

Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi – 110029, INDIA.

Purpose: The study was conducted to determine the association between asymptomatic bacteriuria (ABU) in pregnancy and the clinical profile, causative organisms and their antibiotic resistance pattern. Methods: A total of 500 pregnant women who presented for a regular antenatal care were studied. Clinical details were collected and recorded in the pretested proforma. The urine culture was carried out as per standard technique. Isolates were identified and antibiotic susceptibility pattern was established. Results: Out of 500, significant bacteriuria was noted in 42 women (8.4%). Escherichia coli was the predominant organism isolated (64.3%) followed by Klebsiella spp. (11.9%). Fosfomycin (100%) and Nitrofurantion (92.6%) were found to be the most effective antibiotic against the urinary isolates. Ampicillin, Cotrimoxazole and Norfloxacin antibiotics which were used to treat urinary tract infection (UTI), have shown more resistance. No statistically significant association was observed between the occurrence of bacteriuria and the clinical profile like age, trimester, gravid and parity status of pregnant women. Conclusion: Asymptomatic bacteriuria is not uncommon among pregnant women. Thus, routine urine cultures and antibiotic susceptibility testing must be done to detect and treat it. Oral Nitrofurantoin and Fosfomycin are the antibiotic of choice for treatment of UTI in pregnant women.