Official Journals By StatPerson Publication

 

Abstract Background and Objective: Dyspepsia is an extremely common symptom with prevalence in the community of approximately 30%. Approximately 50% of world’s population is estimated to be infected with H. pylori. The prevalence of H. pylori is higher in developing than in developed countries. H. pylori prevalence differs from one country to another and may differ between different ethnic, social, or age groups within the same country. Objective: 1. To study the presence of H.pylori infection in patients with dyspepsia 2. Relationship between ulcer / non ulcer dyspepsia and H.pylori infection. 3. Gastroscopic findings in patients presenting with dyspepsia. Methods: A prospective clinical study of 100 patients visiting the Hospital for dyspeptic symptoms meeting the inclusion criteria were included in the study. Detailed history was taken and patients underwent upper GI endoscopy and blood was withdrawn for estimation of haemoglobin, blood group, Rh factor and IgG ELISA for H.pylori. Results: 66 males and 34 females participated in the study with mean age of 39.6 years (SD - 12.10). 58% of study population tested positive for H.pylori infection by detection of IgG antibodies against H.pylori in blood by ELISA technique. 37% of the study population had ulcer in stomach or duodenum as detected by upper GI endoscopy. Interpretation and Conclusion: Data from this study shows that H.pylori infection is detected in a significant number of patients presenting with dyspeptic symptoms with no other specific risk factors for acid peptic disease (eg: alcohol, smoking, usage of NSAID’s).

Key Word: Dyspepsia, H.Pylori, IgG ELISA, Ulcers

 

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