Abstract    Introduction: Coronary artery disease is a major cause of myocardial infarction. Abnormal Homocysteine level appear to damage the arterial lining leading to atherosclerosis and ultimately to coronary artery disease. Objective: To study the serum homocysteine level in acute myocardial infarction in young patients in Nanded district. Methods and Material: The serum homocysteine was done in 40 patients of MI and 40 healthy controls belonging to age group 35-45 yrs. Results: According to our study mean Homocysteine in normal healthy controls was 12.56 ± 3.1 µmol/L while in AMI patients mean homocysteine was 23.97 ± 9.7 µmol/L. The level of serum homocysteine level in myocardial infarction patients was significantly high. Conclusion: This study indicated a strong positive correlation of raised homocysteine level with myocardial infarction in patients of Nanded district and as possible risk factor for myocardial infarction.

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