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Abstract    Background: Surgical wound infections are increasingly becoming difficult to manage with the rise of drug resistance among the bacterial isolates. With the use of implants for open reduction and internal fixation which are foreign bodies, trauma surgeries remain a grave risk for infection. Aims: To find the causative agents of surgical wound infections and their antibiotic susceptibility pattern among orthopaedic patients and also to observe changing trend of infection pattern. Materials and Methods: During six years of the study (2009-2014) 10808 pus or aspirate samples from surgical site wound infections of the patients attending the OPD and wards of the orthopaedic department were processed in the laboratory. Samples were cultured and identification was done using conventional methods. The antibiotic susceptibility test was performed using the Kirby Bauer’s disk diffusion method as per Clinical Laboratory Standards Institute 2013 guidelines. The ESBL and MRSA were detected by standard methods. Results: The overall culture positivity rate was estimated at 53%, out of which 46% were from the inpatients and 54% from the OPD. Staphylococcus aureus was isolated in 34%, out of which 48% were methicillin resistant Staphylococcus aureus (MRSA). Among the gram-negative bacteria, P. aeruginosa (18%), Klebsiella pneumoniae (18%), E coli (11%) and Acinetobacter baumanii(8%)were isolated. A gradual increase in the antibiotic resistance against the commonly used drugs was observed in both the gram-positive and gram-negative flora. Conclusion: The incidence of wound infections in the orthopaedic cases is high. The drug resistance is an emerging problem.

Keywords: Antibiotic resistance, Orthopaedics, Surgical wound infection.


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