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Abstract               Gastrointestinal stromal tumours (GISTs) are mesenchymal neoplasms that account for approximately 2% of all malignant gastric tumors. GISTs range from indolent, hardly proliferating to fast-growing, recurring and metastasizing lesions. Malignant potential and prognosis of these tumors are based on tumor size and mitotic count. The primary treatment of GIST consists of surgical excision of the tumor with a good margin of normal tissue. Specific targeted therapy (Imatinib mesylate) is effective in most cases with KIT mutations and many with PDGFRA mutations. In this case report we present a case of mixed type of GIST with high malignant potential.

                Key Word: Gastrointestinal stromal.



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