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Abstract Introduction: Dengue is one of the most important arboviral infections of humans. World-wide incidence of Dengue fever (DF) and Dengue hemorrhagic fever (DHF) has increased dramatically in recent decades. Aims and Objectives: To study Clinical and Laboratory Features with Outcome in Patients of Dengue Viral Infection. Methodology: This prospective observational study was carried out after clearance from local ethical committee from November 2013 to November 2015 in tertiary care hospital. All eligible patients of either sex according to inclusion/exclusion criteria who were admitted in the hospital due to acute febrile illness were evaluated for clinical and biochemical features of DF, DHF and DSS. The WHO classification and case definitions were used to classify the disease as DF, DHF and DSS. Statistical Package for Social Sciences (SPSS) version 14.0. Means and standard deviations were calculated for continuous variables and frequencies for categorical variables. Cross tabulation was done to determine relationship between different variables and P-values were calculated as the test of significance. The clinical manifestations and laboratory findings of each group of illness were compared using the Fisher's exact test for proportions. Result: Among 178 cases of Dengue viral infection, there were 96 (53.93%) male patients and 82(46.07%) female patients. The ratio of male to female was 1.17. Maximum number of males and females were both from the age group of 11-20 years. The Cases were more common in Males as Compared to Females (53.93%) and (46.07%) respectively. In this study the most common features amongst the non-survivor dengue fever infection patients were fever (100%), headache (87.5%), restlessness (87.5%), pallor (75%) and facial puffiness (62.5%). Restlessness, headache, pallor and facial and Laboratory Parameters like Deranged KFT (25%) and Deranged LFT (50%) puffiness were statistically significant. Conclusion: It could be concluded from our study that: The prevalence of disease was more in younger population with more gender predisposition towards males. Most common features amongst the non-survivor cases were fever, pallor, restlessness, vomiting, facial puffiness and Deranged KFT and LFT.

Key Words: Dengue fever (DF), Dengue hemorrhagic fever (DHF), Deranged KFT, Deranged LFT.



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