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Objective: To assess and compare the early and intermediate recovery characteristics after anaesthesia with sevoflurane and desflurane Study Design: Randomized controlled trial Materials and Method: After institutional ethics committee approval and written informed consent 100 healthy patients of ASA 1 and 2 were selected and divided into two groups each consisting of 50 patients. in group (S) anesthesia was maintained by Sevoflurane and in group (D) anesthesia was maintained by Desflurane, the aim was to assess and compare the early and intermediate recovery characteristies. It was observed that intraoperative hemodynamic parameters did not differ in the two groups (p >o.o5). The time to eye opening, Time of first response to commond, Time of extubation( P<0.0001) which was highly significant, and SPEED Criteria was higher after Desflurane anesthesia than after Sevoflurane anesthesia at 0 min and 5 min(P=0.03)At 10,15,20,25,30,and 60 min SPEEDS Criteria comparable in the two groups. Conclusion: Both Desflurane and Sevoflurane produce similar hemodynamic changes, the early recovery was significantly faster after Desflurane,

Keyword: Volatile anaesthetic: sevoflurane, Desflurane Recovery: Early, Intermediate, Laparoscopic surgery.






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