[Abstract] [PDF] [HTML] [Linked
International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109
Volume 4, Issue 3, 2012 pp 134-136
A Crossectional Study of Glycosylated Haemoglobin (HbA1c) Values in Type II Diabetes Mellitus & its Relationship with Lipid Profile and Diabetes Complications
Ahmed Munibuddin1, Khaled M Badaam2, Zingade U. S.3
1,2Assistant Professor, Department of Physiology, Government Medical College, Aurangabad 431 001 (MS) INDIA.
3Professor, Department of Physiology, B. J. Medical College, Pune (MS) INDIA.
Academic Editor: Dr. Aher K. R.
Abstract: The present study was carried out with an objective to find out the correlation of glycosylated haemoglobin with blood sugar, serum cholesterol and triglyceride levels in patients having type II diabetes with and without complications. In this study 30 diabetic patients without any complication and 40 diabetic patients with microangiopathies, in which 20 were having diabetic retinopathy and 20 having diabetic nephropathy with retinopathy were compared with 30 normal subjects of same age group acting as a control group. Blood glucose levels (Fasting & Post meal), glycosylated haemoglobin, serum cholesterol and triglyceride were estimated in these three groups. In diabetes with microangiopathy the fasting blood glucose level was 232.92 ± 20.03, post-meal blood glucose level was 267.96 ± 25.68, HbA1c % was 10.48 ± 1.22, serum cholesterol 262.0 ± 11.30 and triglyceride 174.60 ± 7.87. In diabetes without any complications the fasting blood glucose level was 163.07 ± 20.31, post-meal blood glucose level was 208.33 ± 18.50, HbA1c % was 7.62 ± 0.69, serum cholesterol 213.66 ± 11.51 and triglyceride 151.08 ± 10.86. And in non-diabetic control subjects the fasting, post-meal blood glucose levels, HbA1c% serum cholesterol and triglyceride were 95.12 ± 9.31, 140.15 ± 9.43, 4.99 ± 0.98, 164.75 ± 13.39 and 120.0 ± 9.21 respectively. It was observed that the glycosylated haemoglobin % is more in diabetics and much more in diabetics with complications, and this increase in glycosylated haemoglobin % has a positive correlation with fasting, post-meal blood glucose, serum cholesterol and triglyceride levels.