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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 5, Issue 2, 2012 pp 68-70

Research Article

Plasma Osteopontin Level in Ischemic Heart Disease

Sudhir P. Sase1, Jayshree V. Ganu2, Ashok N. Bhupali3, Pramod Shinde4

1Assistant Professor, Bharati Vidypeeth Deemed University Dental College and Hospital Sangli, Maharashtra, INDIA.

2Associate Professor, Government Medical College Miraj, Sangli, Maharashtra, INDIA.

3Interventional Cardiologist, Apple Heart Institute, Kolhapur, Maharashtra, INDIA.

4Specialist Hematology, Qatif Central Hospital, SAUDI ARABIA.

Academic Editor:  Dr. Aher K. R.



The aim of the present study was to evaluate the association between plasma Osteopontin (OPN) levels and ischemic Heart disease (IHD).OPN is a bone related protein present within the atherosclerotic plaque. OPN is 44kDa glycoprotein which is implicated in the regulation of biological phenomenon including atherosclerosis. Plasma OPN level was measured from 115 patients (age36 to 66 years) who underwent coronary angiography OPN level of patients with IHD is not significantly different than that of non IHD patients. Hence plasma OPN cannot be considered as an independent risk factor for development of IHD.