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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109
Volume 5, Issue 3, 2013 pp 155-157
Serum ALP & GGT Levels in HIV Positive Patients
Ranjit Patil1, Prathamesh Kamble2, Uplabdhi Raghuwanshi3
1 Professor, Department of Medical Biochemistry, Dr. Ulhas Patil Medical College, Jalgaon, Maharashtra, INDIA.
2 Assistant Professor, Department of Physiology, B. J. Government Medical College, Pune, Maharashtra, INDIA.
3 Ph.D. Student, B. J. Government Medical College, Pune, Maharashtra, INDIA.
Academic Editor : Dr. Aher K.R.
Analysis of liver-associated enzymes may also help focus the diagnostic workup. The present study attempts to assess the following in HIV positive patients – (1) To study whether the liver functions are deranged in HIV positive patients by estimating the serum ALP & GGT levels. (2) Whether or not it can be used as a diagnostic & prognostic tool. The mean ± SD serum ALP & GGT in control group was demonstrated to be 43.12 ± 4.13 IU/L & 19.52 ± 2.93 IU/L, according to the present study, which was found to be increased to 129.5 ± 126.12 IU/L (p < 0.01) & 57.27 ± 26.35 IU/L (p<0.01) in HIV positive patients. The increase was found to be statistically significant for ALP & GGT. It could be concluded that the liver function tests are deranged in HIV positive patients as compared to control. The deranged serum ALP & GGT levels may identify patients requiring further investigations thus can be used as a diagnostic & prognostic tool.