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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 6, Issue 3, March 2013 pp 115-118

Research Article

Comparison of Prostaglandin E2 Vaginal Gel versus Intracervical Foley’s Catheter Balloon for Induction of Labour


Dileep P. Javadekar1*, R. P. Patange2, Archana Rokade3

{1, 3 Assistant Professor, 2Professor & HOD} Department of OBGY. KIMS, Malakapur, Karad, Maharashtra, INDIA.


Academic Editor : Dr. Aher K.R.



At times, despite an unripe cervix, induction of labor may be needed. In these cases, a safe and suitable method should be considered for cervical ripening and pregnancy termination. The aim of this study is the comparison of vaginal Dinoprostone Gel (PGE2) with Foley catheter for cervical ripening and induction of labor. This randomized clinical trial was performed on 216 pregnant women. These women were randomly divided into two groups: Dinoprostone (including 98 patients) and Foley catheter (including 118 patients). For the first group, 0.5mg.Dinoprostone vaginal gel was administered every 6 hours up to maximum 2 doses. For the second group, Foley catheter 18 F, inflated with 50 cc of sterile water, was placed through the internal os of the cervix. Data was analyzed and p < 0.05 was considered statistically significant. Two groups were similar in the view of demographic characteristics, cesarean indications, maternal and fetal outcomes and neonatal outcomes. Vaginal delivery was significantly higher in Dinoprostone group (89.9 vs. 62.7, p < 0.01). The mean of delivery time was significantly shorter in Dinoprostone  group (11.08 ± 5.6 vs. 13.6 ± 16.0 h, p < 0.05). In the cases of pregnancy termination and unripe cervix, two methods of Dinoprostone and Foley catheter were considered suitable, but it seemed that Dinoprostone decreases the delivery time and was needed for the cesarean section.