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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 7, Issue 2, June 2013 pp 60-62

Research Article

Evaluation of Role of Creatine Kinase Activity as a Diagnostic Tool for Thyroid Function

Shamali Jungare¹, Ajay Jungare², Sanjay Sonone³

{¹Assistant Professor, ³Professor, Department of Biochemistry} {²Assistant Professor, Department of Pathology}

Academic Editor : Dr. Aher K.R.

Thyroid dysfunctions are common endocrine disorders. Thyroid function tests which are usually done are measurement of blood hormones - triiodothyronine (T3), thyroxine (T4) and thyroid stimulating hormone (TSH) which are affected by various non-specific conditions. Therefore the present study was done to evaluate the role of alternative biochemical parameter - creatine kinase (CK) in diagnosing thyroid disease.  Thyroid function and creatine kinase activity was measured in 50 patients with thyroid disorders. The decreased levels of T3, T4 and increased levels of TSH in hypothyroid patients is well established but whether there is any correlation of creatine kinase with hypothyroidism is not well established. Our study showed that in hypothyroid patients there is significant increase in CK and finding were reversed in hyperthyroid patients. Thus measurement of CK levels may act as a good tool to diagnose thyroid disorders.