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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 7, Issue 3, July 2013 pp 124-126

Research Article

A Qualitative Analysis of Efficacy of Multivitamin and Micronutrient Supplementation on Semen Parameters in Patients with Primary Infertility:

A Prospective Randomized Control Study


J. N. Muneshwar1, M. S. Baig2, Deepali Kaderkar3, Khan S. T.4, Shubhangi Deshmane5

Department of Physiology, Government Medical College Aurangabad, Maharashtra, INDIA.


Academic Editor : Dr. Aher K.R.



Background: Studies have shown that seminal antioxidant capacity is suppressed in infertile men with high reactive oxygen species (ROS) levels as compared to men with normal levels of ROS. Controversy exists, as to whether the high ROS levels detected in semen of infertile men are due to increased ROS production or decreased ROS scavenging or both. Aim: The study was undertaken to evaluate the efficacy of antioxidants multivitamin and micronutrient supplementation on semen parameters in patients with primary infertility. Methods: n =30 patients, between 25 - 35 years, with primary infertility were enrolled for the study. Standard doses of multivitamin and micronutrient supplements were given twice daily for 6 months. Semen parameters including sperm count, motility and morphology were studied before and after the therapy. Paired‘t’ test was used for statistical analysis. Results: The sperm count, and motility improved significantly (P< 0.05) after multivitamin and micronutrient therapy. Conclusion: Multivitamin and micronutrient supplementation improves the seminal parameters and might have a place as an additional supplement in the treatment of male infertility.