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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 7, Issue 3, July 2013 pp 127-128

Research Article

A Prospective, Randomized Parallel Control Study to Evaluate the Nerve Conduction Velocity in Patients with Essential Hypertension


Shubhangi Deshmane, Jaya Muneshwar, S. T. Khan, Deepali Kaderkar

Department of Physiology, Government Medical College, Aurangabad, Maharashtra, INDIA.


Academic Editor : Dr. Aher K.R.



Background – Hypertension has been identified as a risk factor associated with neuropathy and micro vascular diseases. Data on nerve conduction velocity in patients with essential hypertension is inconsistent. Some studies have observed a reduction in the nerve conduction velocity in essential hypertension but subsequent studies failed to demonstrate such difference. Objectives - The aim of the study was to evaluate the motor and sensory conduction velocity of median nerve in patients with essential hypertension. Methods - The study was carried out in the Department of Medicine, Government Medical College Aurangabad. n =30 patients of essential hypertension between the ages of 40-60 years of either sex along with 30 age and sex matched normotensives as controls were enrolled for the study. Patients with diabetes, renal insufficiency, alcoholism, vascular diseases, or other conditions known to cause peripheral neuropathy were excluded from the study. The motor and the sensory conduction velocity of median nerve were studied using standard techniques. Statistical Analysis – Student’s ‘t’ test was used for the intergroup comparison. Results - The sensory nerve conduction velocity (m/s) in normotensives group was 60 ± 2.82 and hypertensive group was 60.32 ± 2.78. The motor nerve conduction velocity in normotensives was 58.60 ± 4.10 and in hypertensive group was 57.75 ± 4.30. When compared, these findings motor and sensory nerve conduction velocity in normotensives and hypertensive were not statistically significant (p> 0.05). Conclusion - Extensive studies will be required considering all grades of hypertension for confirmative analysis.