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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 7, Issue 3, July 2013 pp 105-109

Research Article

The Correlation between Carotid Arteries Intimal Thickness with Microalbuminuria of Essential Hypertension

 

Syed Umar Quadri1, Sunil Agrawal2, Mrunalini Motlag3

1Assistant professor, Department of Medicine, Mahatma Gandhi Missions Medical College Aurangabad, Maharashtra, INDIA.

{ 2Associate professor, 3Assistant professor} Department of Medicine, Indira Gandhi Missions Government Medical College Nagpur, Maharashtra, INDIA.

 

Academic Editor : Dr. Aher K.R.

Abstract

 

Hypertension is major risk factor for the development of cardiovascular diseases and stroke, its impact on end stage renal failure is greatest. Microalbuminuria is frequently seen in patients with established essential hypertensive and which is predictor of a higher risk of cardiovascular dysfunction. In this study, 60 essential hypertensive subjects were included; these were divided in two groups, 30 essential hypertensive subjects with Microalbuminuria and 30 essential hypertensive subjects without Microalbuminuria. In essential hypertension subjects with Microalbuminuria systolic blood pressure 159.73±10.28 was significantly [p=0.02] greater than in subject without Microalbuminuria 153.60±9.60. The mean Diastolic blood pressure 93.27±6.76 in essential hypertension with Microalbuminuria was significantly [p=0.04] greater than subjects without Microalbuminuria 90.66±4.37.Also essential hypertension subject with Microalbuminuria in Body Mass Index [p=0.000], serum cholesterol level [p=0.008], serum Triglyceride [p=0.006] were significantly greater than essential hypertension subject without Microalbuminuria. The Carotid Artery Intima Medial Thickness in essential hypertensive subject with Microalbuminuria 0.871±0.112 was greater than 0.72±0.085 without Microalbuminuria and this difference was statistically significant [p=0.000]. The correlation in essential Hypertensive with Microalbuminuria of carotid Artery Intima Medial Thickness with Systolic Blood Pressure, Urinary Microalbumin was positively related and statistically significant. In without Microalbuminuria the correlation between carotid Artery Intima Medial Thickness with Systolic Blood Pressure, Serum Triglycerides, Urinary Microalbumin, LDL and VLDL was positively related and statistically significant.