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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 8, Issue 1, August 2013 pp 22-26

Research Article

Correlation of Diabetic Retinopathy with Serum Lipids

 

Smita Dileep Javadekar1, Sindal Deokrishna2, Karambelkar V. H.3, Pooja Agrawal4

{1Associate Professor, 2Professor and H.O.D., 3Professor, 4Resident}

Dept of Ophthalmology, KIMSDU, Malkapur, Karad, Maharashtra, INDIA.

 

Academic Editor : Dr. Aher K.R.

Abstract


Aim: To find out the Correlation of Diabetic retinopathy with serum lipids in Type 2 diabetic subjects. Settings and Design: Cross sectional nonrandomized study. Materials and Methods: 311 patients with more than 5 years of Type 2 diabetes were assessed for presence and severity of retinopathy and were co related with age, sex, duration of DM and serum lipids. Diabetic Retinopathy was diagnosed by fundus examination and classified according to the Early Treatment Diabetic Retinopathy Study (ETDRS) grading system. Results: Overall 76.5% (238) had DR and 23.5% (73) had no Diabetic Retinopathy. The mean serum cholesterol (P<0.05), serum triglycerides (P <0.05) and non-high-density lipoprotein (HDL)-cholesterol (P <0.05) concentrations were higher in subjects with Diabetic Retinopathy compared with those without Diabetic Retinopathy. Significant association of triglycerides (P< 0.05) and LDL-cholesterol with clinically significant macular edema (CSME) (P< 0.05). Conclusion: Significant association is found of dyslipidaemia with Diabetic Retinopathy and CSME.