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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 8, Issue 2, August 2013 pp 100-102

Research Article

Association of IL-6 with Diabetes Mellitus in Indian Population from Navi Mumbai

Vidhate D. A.¹, Thomas J.², Gupte A. M.³

{¹Department of Biochemistry, ²Department of Cardiothoracic Surgery} Pad. Dr. D.Y. Patil Medical College and Research Centre, Nerul, Navi Mumbai, Maharashtra - 400706 INDIA.

Academic Editor : Dr. Aher K.R.

Diabetes has already reached an epidemic level in India. Chronic inflammation has been considered as a culprit for setting pathophysiological changes which results in insulin resistance and type 2 diabetes mellitus. IL-6 is one of the several proinflammatory cytokines that have been associated with type 2 diabetes. Very few studies on role of circulatory IL-6 in diabetes have been published in Indians. This study aims to determine the serum levels of IL-6 in diabetic patients and compare them with healthy controls. We hypothesized that circulating IL-6 levels increases in diabetes due to underline chronic inflammation. Conclusion: Our results concluded that increased serum IL-6 levels compared to normal controls might be associated with inflammation related pathophysiology in type 2 diabetes.