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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 8, Issue 3, October 2013 pp 240-243

Research Article

Total Intravenous Anaesthesia with Propofol for Intra-Abdominal Surgeries


V. P. Dayananda1, J. Vasanthakumar2, G. S. Venkatesh3

1,2Assistant Professor, Department of Anesthesiology, BMC and RI, Bangalore, Karnataka, INDIA.

3Professor, Department of Anesthesiology, MMC and RI, Mysore, Karnataka, INDIA.


Academic Editor : Dr. Aher K.R.


Introduction: Total intravenous anaesthesia is a technique involving infusion and maintenance of anaesthetic state with intravenous drugs alone. But no agent has all the characteristics of ideal TIVA agent. Propofol has three important characteristics of ideal TIVA agent, i.e. rapid induction, rapid metabolism and rapid recovery. In this communication we studied the characteristics of propofol in total intravenous anaesthesia in various intra-abdominal surgeries. Methods: A total 50 patients aged 18 to 60 years belonging to ASAgr 1 and gr 11 undergoing various elective intra abdominal surgery took part in this prospective study. All patientswere induced with 2mg/kg body weight 1% propofol after premedication 0.03 mg midazolam and pentazocine. Anesthesia maintained with 0.1% propofol at rate of 100Ug/kg/min with 100% oxygen and incremental dose muscle relaxant. Based on haemodynamic sings and sympathetic over activity dose of propofol was adjusted in intraoperative period. At skin closure infusion was discontinued and neuromuscular blockade reversed. Result: TIVA with propofol enabled smooth and rapid induction in all patients with induction time of 29.7 seconds. In maintenance phase propofol provides adequate depth of anaesthesia assessed by haemodynamic changes and sympathetic over activity in 46 (92%) of the patients. Four patients (8%) needed higher dose of infusion to maintain adequate depth of anaesthesia. Recovery was good with short response time of 10.3 minutes and orientation time of 14.54 minutes. Conclusion: Propofol based TIVA provides smooth and rapid induction and acceptable haemodynamic status during maintenance period in most of the patients.All patients were alert and clear headed with smooth recovery from anaesthesia effect.