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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 9, Issue 1, November 2013 pp 129-135

Research Article

Retrospective Study of Various Maternal Factors Responsible For Meconium Stained Amniotic Fluid and Its Impact on Perinatal Outcome


Manohar R.*, Kavyashree G.#

*Assistant Professor, #Associate Professor, Department of OBGY, Mandya Institute of Medical Sciences, Mandya, Karnataka.

Academic Editor : Dr. Aher K.R.



Meconium is derived from the Greek word “meconium-arion”1, meaning “opium-like”. Many maternal factors contribute to passage of meconium before birth which includes maternal age, prolonged gestation, anaemia, hypertension, ante-partum haemorrhage and others2.Objectives: To find out the various maternal factors responsible for meconium stained amniotic fluid(MSAF), intrapartum complications and outcome of labor in cases of meconium stained amniotic fluid and its impact on perinatal morbidity and mortality. Materials and methods: It is a retrospective study of 2840 cases of consecutive deliveries from January 2013 to June 2013 in Mandya Institute of Medical Sciences,,Mandya to know the incidence of meconium stained amniotic fluid in these cases, to evaluate the antepartum and intra-partum factors responsible for meconium stained amniotic fluid and also to study the labour outcome with regard to perinatal morbidity and mortality as a result of meconium stained amniotic fluid. Results: Out of 2840 deliveries, 571 cases of meconium stained amniotic fluid were studied. The incidence of meconium stained amniotic fluid was 20.1%. Incidence of MSAF was more commonly seen in pregnancy with crossed EDD( >40weeks), oligohyramnios, , preeclampsia, PROM, anaemia. 77 cases of Meconium aspiration syndrome(MAS) were admitted to NICU out of which there were 15 perinatal mortality. 13 cases of MAS were associated with thick meconium and 2 cases with moderately thick meconium stained liquor. Severe perinatal asphyxia(8 cases) was most common cause for perinatal mortality followed by hypoxic ishaemic encephalopathy(4), respiratory distress syndrome(2) and septicaemia(1). Conclusion: Meconium stained amniotic fluid was associated with perinatal morbidity and mortality. It signifies the need for prevention and treatment of various antepartum and intrapartum complications, which were responsible for intrauterine hypoxia and meconium stained amniotic fluid.