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International Journal of Recent Trends in Science and Technology, ISSN 2277-2812 E-ISSN: 2249-8109

Volume 9, Issue 2, December 2013 pp 171-173

Research Article

Study of Thyroid Profile in First Trimester of Pregnancy


Shamali Jungare1, Sanjay Sonune2

{1Assistant Professor, 2Professor} Department of Biochemistry

Government Medical College and Hospital, Akola, Maharashtra, INDIA.


Academic Editor : Dr. Aher K.R.



Thyroid disorders are common in pregnancy. There is an increasing interest in identifying changes in thyroid function during pregnancy due to the role of thyroid function in maintaining a viable pregnancy and contributing to healthy offspring. Thus the present study was conducted for evaluation of thyroid function during first trimester of pregnancy. We examined total 50 pregnant women in first trimester and 50 age matched control for thyroid factor. We found there is significant elevation in serum levels of triiodothyronine (T3) and thyroxine (T4) in first trimester of pregnancy as compared to control group. Mean thyroid stimulating hormone (TSH) in this group was suppressed but their level doesn’t match with elevated thyroid hormones. In first trimester of pregnancy elevated thyroid hormones according to the manufacturers reference range which suggests hyperthyroidism is actually an extra requirement of thyroid hormones by growing fetus. Also it is suggested that to avoid misdiagnosis of hyperthyroidism in pregnancy, specific trimester related reference interval should be established for particular region.